The effect of sex and age of the donor on the outcome of transfusion recipients
ISBT Education. Middelburg R. 06/06/18; 218865 Topic: Donor management
Disclosure(s): I have nothing to disclose.
Dr. Rutger Middelburg
Dr. Rutger Middelburg
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Learning Objectives
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After viewing this presentation, the participant will be able to:
1. Describe quantitatively the contribution of previously pregnant blood donors to mortality among male red blood cell transfusion recipients in the Netherlands.
2. Describe how differences in the composition of patient and donor populations could explain differences between findings from different studies on this subject.
3. Describe how increased knowledge about the biological mechanism may help remove this risk from the blood supply without the need to defer any previously pregnant donors.
1. Caram-Deelder C, Kreuger AL, Evers D, de Vooght KMK, van de Kerkhof D, Visser O, Péquériaux NCV, Hudig F, Zwaginga JJ, van der Bom JG, Rutger A. Middelburg. Association of Blood Transfusion From Female Donors With and Without a History of Pregnancy With Mortality Among Male and Female Transfusion Recipients. JAMA. 2017 Oct 17;318(15):1471-1478.
2. Rutger A. Middelburg, Ernest Briët, Johanna G. van der Bom. Mortality after transfusions, relation to donor sex. Vox Sang. 2011 Oct;101(3):221-9.
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